Mikkelsen achieved worldwide recognition for playing the main antagonist Le Chiffre in the twenty-first James Bond film, Casino Royale (2006).
He rose to fame in Denmark as an actor for his roles such as Tonny in the first two films of the Pusher film trilogy (1996, 2004), Detective Sergeant Allan Fischer in the television series Rejseholdet (2000–2004), Niels in Open Hearts (2002), Svend in The Green Butchers (2003), Ivan in Adam's Apples (2005) and Jacob Petersen in After the Wedding (2006). Mads Dittmann Mikkelsen ( Danish: ⓘ born 22 November 1965) is a Danish actor and former gymnast and dancer.